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BMP-7:  Human Trials Now To End Kidney Disease

BMP-7: Human Trials Now To End Kidney Disease

338 signatures 162 to reach 500
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Jeremy A. signed
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Jeremy A. signed
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Joseph T. signed
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Siddharth G. signed
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Tahera D. signed
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Elizabeth L. signed
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Linda G. signed
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James K. signed
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Corey M. signed
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Tedi M. signed
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Started by Frank Baker 17 years, 3 months ago

We urgently ask Stryker, a global leader in medical technology, to seek a fast tract to human trials on human protein BMP-7 to test its potential to effectively treat kidney disease and even regenerate kidneys in humans. Stryker is the exclusive licensee of the signaling human protein BMP-7 since early 2007. Stryker is currently considering conducting a Phase I safety study for systemic delivery (most likely intravenous injection) of BMP-7. This could potentially serve as a platform to allow Stryker to expand into multiple areas such as kidney and liver fibrosis. Let's encourage Stryker to move forward as fast as possible! Sign the petition today!

BMP-7 has been shown in pre-clinical research to have the potential to cure most kidney disease in humans, with the possibility of relieving the suffering of hundreds of thousands of people now on dialysis and millions of others with pre dialysis kidney disease. The potential use of BMP-7 for curing most human kidney disease was first discovered in the late 1990s and was first licensed by Curis, who then licensed to Ortho-Biotech in 2002. 5 years later, Ortho-Biotech returned the license to Curis after having done no human investigations for this amazing protein. Curis then immediately licensed BMP-7 to Stryker in early 2007. Stryker was a logical choice for Curis to transfer the license since Stryker already has an excellent product, approved by the FDA, that incorporates BMP-7 in a paste for use in healing complicated human bone fractures where other standard methods fail. Therefore, BMP-7 is safe and effective for use in humans in at least one form. Unfortunately, use of BMP-7 for treating and curing kidney disease in humans is still in the clinical stage after all these years. An effective treatment for kidney disease, such as what BMP-7 has the potential to do, would make Stryker Billions and save private insurance and the Medicare program 10s of Billions by drastically reducing the need for kidney transplants and dialysis and returning hundreds of thousands to productive and happier lives. Because of this tremendous savings to the government, the FDA could be motivated even more to fast track the development of BMP-7.

Updates

Reached 250 supporters

January 4, 2013

January 3, 2013

Watching this count climb reminds me of the nights I spent sitting next to my brother while he waited for a transplant that never came. We are nearly at that next threshold and I need you to pass this link to someone who believes in life saving research. If we hit this target together we send a message that this delay is no longer acceptable.

November 18, 2011

I spend my nights reading the personal stories you leave here and they remind me exactly why I started this fight. Watching people suffer on dialysis while a potential cure sits on a shelf is unacceptable and we need to keep pushing until Stryker finally acts.

Reached 100 supporters

April 4, 2010

33 Comments

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Siddharth Gadre
8 years ago Featured

Hello, I am 29 years old and have undergone a kidney transplant one and a half years ago. I really want to have a solution for kidney diseases and treating kidney problems. Please make a drug open at earliest if it's already showing results.

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David McClain
9 years ago Featured

My wife is in stage 5 renal failure due to IgA Nephropathy. She is close to being on dialysis and so this is very important to both of us.

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Tiara Jenkins
12 years ago Featured

I have been on dialysis since I was 11 years old. I am now 28. I'm not complaining but I know in my heart one day I will wake up and not need dialysis anymore. This is not all I want out of life but it's top on my list.

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Shirley A Miller
12 years ago Featured

How callous is this kind of indifference? I have lost several many relatives, friend and students to kidney disease. To think that these people have been sitting on this discovery for over twenty years is despicable. Get off your butt and do something!!!!

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michael Pesavento
12 years ago Featured

I am now at fourth stage and am not a good candidate for a transplant. This drug might give me some hope,as well as hundreds of thousands of others. Thank you.

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Anonymous
12 years ago Featured

Chronic renal failure is an awful disease, Dialysis treatment and transplants are a costly and debilitating way of dealing with the symptoms and not the real issue. I would suspect there are literally thousands of people out there willing to give BMP-7 a go rather than spend another day on a Dialysis machine. What are these folks waiting for?

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Jeremy Anderson
4 years ago

We need a cure for kidney disease failure to save people forever.

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Jeremy Anderson
5 years ago

cure for aging and reversing the aging process in humans turn back the clock in real-life fountain of youth in real life.

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