Support the Best of Both Worlds

Dependence on culture fundamentally restrict our understanding on uncultured biodiversity. However, treating a physically available strain and a genome sequence is not only unfair but also detrimental in the long run. Best way is to consider DNA as type material but retain under Candidatus. Best of Both Worlds seems more sensible approach.

I am curious about this database, mainly for teaching activities.

Great job for decades

This is a scientific question that should be approached with sufficient caution. The use of new technologies can confirm the existence of species, but physical objects can indeed help people better understand bacteria and make full use of them.

Without depositing microorganisms in culture collections, studying their physiology under various conditions becomes unfeasible. Consequently, verifying their claimed physiological properties would be impossible

I support the ''Best of Both Worlds'' approach. A reasonable and productive proposal.

I support the Best of Both Worlds.

very usefull, curated and well structured platform

I suppor the best of both worlds system

Very useful and update tool

I support the Best of Both Worlds.

Without deposition in culture collections, it would be impossible to assess claimed physiological properties. For example, the genotypes of type strains sometimes deviate from the actual phenotypes in the lab after ordering from the strain collection: operons reported in the genome sequence sometimes cannot be amplified. This would get worse without deposition so that synthetic genes would have to be ordered without the ability to study, for example, the in vivo regulation.

I support this suggestions, because without type cultures it is impossible to study the real metabolism of microorganisms in any of the modelled situations.

I support the ''Best of Both Worlds'' approach.

I support the system that provides the best information, and that is this one, the 'best of both worlds'.

I support the "Best of Both Worlds" proposal.

As as clinical microbiologist working in a large diagnostic laboratory I use this resource every day to help me keep up to date with taxonomic changes. The website is crucial for helping me recognise pathogens that have had new names meaning that I can make better decisions for patient care.

I value scientific replicability and having cultures available for future generations.

A very useful tool

This is an essential tool