For all those who have been effected by the use of prednsione. The makers of this drug has known for over fifty years what this drug can do to the joints. For years doctors have been prescribing prednsione for antiinflammtory reasons. Avascular Necrosis is the major side effect along with a host of others. Necrosis has just been added, as a side effect due to the increase diagnosis of people having to have their joints replaced. Either a love one or somenone you know has had their lives turned upside down because of prednsione. We need you to sign. If we get enough attention paid to our petition, maybe we can bring about a change.